FH/Fumarase Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1073-50, EM1073-100

Citations, Manuals and MSDS Available upon request.

Background: Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.

Alternate Name: Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

Source: Mouse

Applications: WB, IF

Dilution: WB 1:3, 000 IF 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 50kDa

Human Gene ID: 2271

Human SWISS Prot NO: P07954

Subcellular Location: Cytoplasm and Mitochondrion.

Research Use Only